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T-Negative was a media science fiction fanzine by Ruth Berman.

T-Negative was one the the first fanzines devoted to Star Trek, released during the original broadcast of the television series. The title of the fanzine refers to the character Mr. Spock's bloodtype, which was T-Negative.

The first issue of T-Negative was released in June 1969. 35 issues were released during the run, which ended in March 1979 with the double issue 35/35.

In her editorial for issue 1, Ruth Berman wrote about starting her fanzine; In November 1968 I starting watching Star Trek, mainly because Juanita Coulson had recommended it so highly in Yandro. By December, I d gotten Eleanor Arnason hooked on it, too, and by December she mmade the classic remark, 'We could write that too'...

Contributors of art work included Alicia Austin (Kevas and Trillium, Kathy Bushman, Juanita Coulson (ST-Phile, Yandro, Tim Courtney, and Greg Jein. Covers were by Tim Courtney, Greg Jein.

Contributors of writing included Astrid Anderson, Eleanor A. Arnason, Nan Braude, Dorothy Jones,

Ruth Berman also published the Sherlock Holmes anthology, SH - sf Fanthology.